Before I went to Rome I investigated all of the options for visiting all the places I wanted to go and happened upon the Omnia card — includes Vatican etc, Roma Cristiano tour bus and the Roma pass which includes 2 visits to big tourist sites such as the colosseum, fast track entry and 3 days travel on all public transport all for £80 The tour route of the Roma Cristiano bus is very similar to most of the other tour buses, operating from 9−6pm. The route commentary is very heavily focused on nearby churches and basilicas, so it may not be for everyone, but for me as a means to get round the city it was fine.